Anti-EGFR therapeutic efficacy correlates directly with inhibition of STAT3 activity

Several agents targeting the epidermal growth factor receptor (EGFR) have been FDA-approved to treat cancer patients with varying tumor types including metastatic colorectal cancer. Many patients treated with anti-EGFR therapy however do not respond and those that do initially respond often acquire...

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Bibliografiska uppgifter
Huvudupphovsmän: Ung, Nelson, Putoczki, Tracy L, Stylli, Stanley S, Ng, Irvin, Mariadason, John M, Chan, Timothy A, Zhu, Hong-Jian, Luwor, Rodney B
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2014
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026085/
https://ncbi.nlm.nih.gov/pubmed/24556630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28179
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