Anti-EGFR therapeutic efficacy correlates directly with inhibition of STAT3 activity

Several agents targeting the epidermal growth factor receptor (EGFR) have been FDA-approved to treat cancer patients with varying tumor types including metastatic colorectal cancer. Many patients treated with anti-EGFR therapy however do not respond and those that do initially respond often acquire...

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Detalhes bibliográficos
Main Authors: Ung, Nelson, Putoczki, Tracy L, Stylli, Stanley S, Ng, Irvin, Mariadason, John M, Chan, Timothy A, Zhu, Hong-Jian, Luwor, Rodney B
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026085/
https://ncbi.nlm.nih.gov/pubmed/24556630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28179
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