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Towards a Therapeutic Reduction of Imatinib Refractory Myeloproliferative Neoplasm-Initiating Cells

Myeloproliferative neoplasms (MPNs) such as chronic myelogenous (CML) and chronic myelomonocytic leukemias (CMML) are frequently induced by tyrosine kinase oncogenes. Although these MPNs are sensitive to tyrosine kinase inhibitors such as imatinib, patients often relapse upon withdrawal of therapy....

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Detalhes bibliográficos
Main Authors: Philips, Steven T., Hildenbrand, Zacariah L., Oravecz-Wilson, Katherine I., Foley, S. Blake, Mgbemena, Victoria E., Ross, Theodora S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025985/
https://ncbi.nlm.nih.gov/pubmed/24240679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.484
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