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Structure–Activity Relationships for Side Chain Oxysterol Agonists of the Hedgehog Signaling Pathway
[Image: see text] Oxysterols (OHCs) are byproducts of cholesterol oxidation that are known to activate the Hedeghog (Hh) signaling pathway. While OHCs that incorporate hydroxyl groups throughout the scaffold are known, those that act as agonists of Hh signaling primarily contain a single hydroxyl on...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American
Chemical Society
2012
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4025875/ https://ncbi.nlm.nih.gov/pubmed/24900386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300192k |
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