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Peptides and Pseudopeptides as SIRT6 Deacetylation Inhibitors

[Image: see text] SIRT6 belongs to the family of histone deacetylases (class III), but it also has mono-ADP-ribosyltransferase activity. SIRT6 is a nuclear sirtuin that has been associated with aging, cellular protection, and sugar metabolism. Despite these important roles for SIRT6, thus far, there...

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Bibliografski detalji
Glavni autori: Kokkonen, Piia, Rahnasto-Rilla, Minna, Kiviranta, Päivi H., Huhtiniemi, Tero, Laitinen, Tuomo, Poso, Antti, Jarho, Elina, Lahtela-Kakkonen, Maija
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2012
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025866/
https://ncbi.nlm.nih.gov/pubmed/24900419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300139n
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