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Synthesis and Anti-influenza A Virus Activity of 2,2-Dialkylamantadines and Related Compounds
[Image: see text] The synthesis of several 2,2-dialkyladamantyl-1-amines through the combination of a Ritter reaction with a Wagner–Meerwein rearrangement from noradamantane alcohols is reported. Several of the novel amines displayed low micromolar activities against several H1N1 influenza virus str...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American
Chemical Society
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4025864/ https://ncbi.nlm.nih.gov/pubmed/24900429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300279b |
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