Polycyclic N‐Benzamido Imides with Potent Activity against Vaccinia Virus

The synthesis and antiviral activity of a series of novel polycyclic analogues of the orthopoxvirus egress inhibitor tecovirimat (ST‐246) is presented. Several of these compounds display sub‐micromolar activity against vaccinia virus, and were more potent than cidofovir (CDV). The more active compou...

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Publicado no:ChemMedChem
Main Authors: Torres, Eva, Duque, María D., Camps, Pelayo, Naesens, Lieve, Calvet, Teresa, Font‐Bardia, Mercè, Vázquez, Santiago
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY‐VCH Verlag 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162373/
https://ncbi.nlm.nih.gov/pubmed/20967819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201000306
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