Antimicrobial Activity of Adenine-Based Inhibitors of NAD(+)-Dependent DNA Ligase

[Image: see text] The relationship between enzyme inhibition and antimicrobial potency of adenine-based NAD(+)-dependent DNA ligase (LigA) inhibitors was investigated using a strain of the Gram-negative pathogen Haemophilus influenzae lacking its major AcrAB-TolC efflux pump and the Gram-positive pa...

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Hlavní autoři: Buurman, Ed T., Laganas, Valerie A., Liu, Ce Feng, Manchester, John I.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2012
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025854/
https://ncbi.nlm.nih.gov/pubmed/24900527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300169x
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