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Synthesis and Antiproliferative Activities of Ottelione A Analogues
[Image: see text] Through the syntheses of its C-1 desvinyl, C-7 methylene, C-7 exocyclic ethylidene, and various C-3 phenylmethyl analogues, the structure–activity relationship of antimitotic ottelione A (4) against tubulin and various cancer cells was established. The results indicated that compou...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4025792/ https://ncbi.nlm.nih.gov/pubmed/24900431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300283f |
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