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Synthesis of Saccharumoside-B analogue with potential of antiproliferative and pro-apoptotic activities

A new series of phenolic glycoside esters, saccharumoside-B and its analogs (9b-9n, 10) have been synthesized by the Koenigs-Knorr reaction. Antiproliferative activities of the compounds (9b-9n, 10) were evaluated on various cancer cell lines including, MCF-7 breast, HL-60 leukemia, MIA PaCa-2 pancr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rayavarapu, Srinuvasarao, Yarla, Nagendra Sastry, Kadiri, Sunanda Kumari, Bishayee, Anupam, Vidavalur, Siddaiah, Tadikonda, Ramu, Basha, Mahaboob, Pidugu, Vijaya Rao, Dowluru, Kaladhar S. V. G. K., Lakappa, Dhananjaya Bhadrapura, Kamal, Mohammad A., Md Ashraf, Ghulam, Tarasov, Vadim V., Chubarev, Vladimir N., Klochkov, Sergey G., Barreto, George E., Bachurin, Sergey O., Aliev, Gjumrakch
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559490/
https://ncbi.nlm.nih.gov/pubmed/28814788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05832-w
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