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Quinolinyl Pyrimidines: Potent Inhibitors of NDH-2 as a Novel Class of Anti-TB Agents
[Image: see text] NDH-2 is an essential respiratory enzyme in Mycobacterium tuberculosis (Mtb), which plays an important role in the physiology of Mtb. Herein, we present a target-based effort to identify a new structural class of inhibitors for NDH-2. High-throughput screening of the AstraZeneca co...
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| Glavni autori: | , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American
Chemical Society
2012
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| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4025736/ https://ncbi.nlm.nih.gov/pubmed/24900541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300134b |
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