Antifungal Spectrum, In Vivo Efficacy, and Structure–Activity Relationship of Ilicicolin H

[Image: see text] Ilicicolin H is a polyketide—nonribosomal peptide synthase (NRPS)—natural product isolated from Gliocadium roseum, which exhibits potent and broad spectrum antifungal activity, with sub-μg/mL MICs against Candida spp., Aspergillus fumigatus, and Cryptococcus spp. It showed a novel...

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Detalhes bibliográficos
Main Authors: Singh, Sheo B., Liu, Weiguo, Li, Xiaohua, Chen, Tom, Shafiee, Ali, Card, Deborah, Abruzzo, George, Flattery, Amy, Gill, Charles, Thompson, John R., Rosenbach, Mark, Dreikorn, Sarah, Hornak, Viktor, Meinz, Maria, Kurtz, Myra, Kelly, Rosemarie, Onishi, Janet C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025731/
https://ncbi.nlm.nih.gov/pubmed/24900384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300173e
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https://ncbi.nlm.nih.gov/pmc/articles/PMC4025731/
https://ncbi.nlm.nih.gov/pubmed/24900384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300173e