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5-Arylbenzothiadiazine Type Compounds as Positive Allosteric Modulators of AMPA/Kainate Receptors
[Image: see text] The potential therapeutic benefit of compounds able to activate AMPA receptors (AMPAr) has led to the search for new AMPAr positive modulators. On the basis of crystallographic data of the benzothiadiazines binding mode in the S1S2 GluA2 dimer interface, a set of 5-aryl-2,3-dihydro...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American
Chemical Society
2011
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| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4025637/ https://ncbi.nlm.nih.gov/pubmed/24900368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200184w |
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