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5-Arylbenzothiadiazine Type Compounds as Positive Allosteric Modulators of AMPA/Kainate Receptors

[Image: see text] The potential therapeutic benefit of compounds able to activate AMPA receptors (AMPAr) has led to the search for new AMPAr positive modulators. On the basis of crystallographic data of the benzothiadiazines binding mode in the S1S2 GluA2 dimer interface, a set of 5-aryl-2,3-dihydro...

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書誌詳細
主要な著者: Battisti, Umberto M., Jozwiak, Krzysztof, Cannazza, Giuseppe, Puia, Giulia, Stocca, Gabriella, Braghiroli, Daniela, Parenti, Carlo, Brasili, Livio, Carrozzo, Marina M., Citti, Cinzia, Troisi, Luigino
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2011
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025637/
https://ncbi.nlm.nih.gov/pubmed/24900368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200184w
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