A novel class of allosteric modulators of AMPA/Kainate receptors

The rapid hydrolysis in vivo of IDRA21 to 2-amino-5-chlorobenzensulfonamide has been demonstrated by microdialysis experiments. The IDRA21 metabolite possess in vitro a biological activity similar to that of IDRA21 itself. Taking 2-amino-5-chlorobenzensulfonamide as lead compound, a novel class of A...

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Библиографические подробности
Главные авторы: Cannazza, Giuseppe, Jozwiak, Krzysztof, Parenti, Carlo, Braghiroli, Daniela, Carrozzo, Marina M., Puia, Giulia, Losi, Gabriele, Baraldi, Mario, Lindner, Wolfgang, Wainer, Irving W.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656388/
https://ncbi.nlm.nih.gov/pubmed/19162477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.12.094
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