Noncompetitive Inhibition of Indolethylamine-N-methyltransferase by N,N-Dimethyltryptamine and N,N-Dimethylaminopropyltryptamine

[Image: see text] Indolethylamine-N-methyltransferase (INMT) is a Class 1 transmethylation enzyme known for its production of N,N-dimethyltryptamine (DMT), a hallucinogen with affinity for various serotonergic, adrenergic, histaminergic, dopaminergic, and sigma-1 receptors. DMT is produced via the a...

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Autores principales: Chu, Uyen B., Vorperian, Sevahn K., Satyshur, Kenneth, Eickstaedt, Kelsey, Cozzi, Nicholas V., Mavlyutov, Timur, Hajipour, Abdol R., Ruoho, Arnold E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2014
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025572/
https://ncbi.nlm.nih.gov/pubmed/24730580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500175p
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