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Adipose tissue insulin resistance due to loss of PI3K p110α leads to decreased energy expenditure and obesity
Adipose tissue is a highly insulin-responsive organ that contributes to metabolic regulation. Insulin resistance in the adipose tissue affects systemic lipid and glucose homeostasis. Phosphoinositide 3-kinase (PI3K) mediates downstream insulin signaling in adipose tissue, but its physiological role...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4025064/ https://ncbi.nlm.nih.gov/pubmed/24691033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00625.2013 |
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