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Large, stratified, and mechanically functional human cartilage grown in vitro by mesenchymal condensation

The efforts to grow mechanically functional cartilage from human mesenchymal stem cells have not been successful. We report that clinically sized pieces of human cartilage with physiologic stratification and biomechanics can be grown in vitro by recapitulating some aspects of the developmental proce...

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Main Authors: Bhumiratana, Sarindr, Eton, Ryan E., Oungoulian, Sevan R., Wan, Leo Q., Ateshian, Gerard A., Vunjak-Novakovic, Gordana
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024923/
https://ncbi.nlm.nih.gov/pubmed/24778247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1324050111
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