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Large, stratified, and mechanically functional human cartilage grown in vitro by mesenchymal condensation

The efforts to grow mechanically functional cartilage from human mesenchymal stem cells have not been successful. We report that clinically sized pieces of human cartilage with physiologic stratification and biomechanics can be grown in vitro by recapitulating some aspects of the developmental proce...

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Detalhes bibliográficos
Main Authors: Bhumiratana, Sarindr, Eton, Ryan E., Oungoulian, Sevan R., Wan, Leo Q., Ateshian, Gerard A., Vunjak-Novakovic, Gordana
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024923/
https://ncbi.nlm.nih.gov/pubmed/24778247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1324050111
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