Radiation-Induced Modulation of Costimulatory and Coinhibitory T-Cell Signaling Molecules on Human Prostate Carcinoma Cells Promotes Productive Antitumor Immune Interactions

We sought to determine if single-dose external beam radiation therapy (EBRT) could modulate the expression signature of T-cell costimulatory and coinhibitory molecules in human prostate cancer (PCa) cell lines in vitro. We investigated the functional impact of irradiated PCa cells with a modulated c...

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Detalhes bibliográficos
Main Authors: Bernstein, Michael B., Garnett, Charlie T., Zhang, Huogang, Velcich, Anna, Wattenberg, Max M., Gameiro, Sofia R., Kalnicki, Shalom, Hodge, James W., Guha, Chandan
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024843/
https://ncbi.nlm.nih.gov/pubmed/24693958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2013.1578
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