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Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice
Mitochondrial function is an important determinant of the ageing process; however, the mitochondrial properties that enable longevity are not well understood. Here we show that optimal assembly of mitochondrial complex I predicts longevity in mice. Using an unbiased high-coverage high-confidence app...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Pub. Group
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4024759/ https://ncbi.nlm.nih.gov/pubmed/24815183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4837 |
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