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Cells of renin lineage take on a podocyte phenotype in aging nephropathy

Aging nephropathy is characterized by podocyte depletion accompanied by progressive glomerulosclerosis. Replacement of terminally differentiated podocytes by local stem/progenitor cells is likely a critical mechanism for their regeneration. Recent studies have shown that cells of renin lineage (CoRL...

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Autores principales: Pippin, Jeffrey W., Glenn, Sean T., Krofft, Ronald D., Rusiniak, Michael E., Alpers, Charles E., Hudkins, Kelly, Duffield, Jeremy S., Gross, Kenneth W., Shankland, Stuart J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024732/
https://ncbi.nlm.nih.gov/pubmed/24647714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00699.2013
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