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Suppression of experimental arthritis by gene transfer of interleukin 1 receptor antagonist cDNA.

Restoration of the impaired balance between pro- and antiinflammatory cytokines should provide effective treatment of rheumatoid arthritis. Gene therapy has been proposed as an approach for delivery of therapeutic proteins to arthritic joints. Here, we examined the efficacy of antiinflammatory gene...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Makarov, S S, Olsen, J C, Johnston, W N, Anderle, S K, Brown, R R, Baldwin, A S, Haskill, J S, Schwab, J H
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1996
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40246/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8552648/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.1.402
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