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Suppression of experimental arthritis by gene transfer of interleukin 1 receptor antagonist cDNA.

Restoration of the impaired balance between pro- and antiinflammatory cytokines should provide effective treatment of rheumatoid arthritis. Gene therapy has been proposed as an approach for delivery of therapeutic proteins to arthritic joints. Here, we examined the efficacy of antiinflammatory gene...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Makarov, S S, Olsen, J C, Johnston, W N, Anderle, S K, Brown, R R, Baldwin, A S, Haskill, J S, Schwab, J H
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40246/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8552648/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.1.402
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