Translation control of TAK1 mRNA by hnRNP K modulates LPS-induced macrophage activation

Macrophage activation by bacterial lipopolysaccharides (LPS) is induced through Toll-like receptor 4 (TLR4). The synthesis and activity of TLR4 downstream signaling molecules modulates the expression of pro- and anti-inflammatory cytokines. To address the impact of post-transcriptional regulation on...

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Autori principali: Liepelt, Anke, Mossanen, Jana C., Denecke, Bernd, Heymann, Felix, De Santis, Rebecca, Tacke, Frank, Marx, Gernot, Ostareck, Dirk H., Ostareck-Lederer, Antje
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024643/
https://ncbi.nlm.nih.gov/pubmed/24751651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.042788.113
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