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Cerebrospinal fluid mitochondrial DNA – a novel DAMP in pediatric traumatic brain injury

BACKGROUND: Danger associated molecular patterns (DAMPs) are nuclear or cytoplasmic proteins that are released from the injured tissues and activate the innate immune system. Mitochondrial DNA (mtDNA) is a novel DAMP that is released into the extracellular milieu subsequent to cell death and injury....

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Detalhes bibliográficos
Main Authors: Walko, Thomas D., Bola, R. Aaron, Hong, John D., Au, Alicia K, Bell, Michael J, Kochanek, Patrick M., Clark, Robert S. B, Aneja, Rajesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024373/
https://ncbi.nlm.nih.gov/pubmed/24667615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000160
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