Population Pharmacokinetics of Bevacizumab in Children with Osteosarcoma: Implications for Dosing

PURPOSE: To describe sources of interindividual variability in bevacizumab disposition in pediatric patients and explore associations among bevacizumab pharmacokinetics and clinical wound healing outcomes. EXPERIMENTAL DESIGN: Prior to tumor resection, three doses of bevacizumab (15 mg/kg) were admi...

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Päätekijät: Turner, David C., Navid, Fariba, Daw, Najat C., Mao, Shenghua, Wu, Jianrong, Santana, Victor M., Neel, Michael, Rao, Bhaskar, Willert, Jennifer Reikes, Loeb, David M., Harstead, K. Elaine, Throm, Stacy L., Freeman, Burgess B., Stewart, Clinton F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024352/
https://ncbi.nlm.nih.gov/pubmed/24637635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-2364
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