Demethylation of the miR-146a promoter by 5-Aza-2’-deoxycytidine correlates with delayed progression of castration-resistant prostate cancer

BACKGROUND: Androgen deprivation therapy is the primary strategy for the treatment of advanced prostate cancer; however, after an initial regression, most patients will inevitably develop a fatal androgen-independent tumor. Therefore, understanding the mechanisms of the transition to androgen indepe...

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Main Authors: Wang, Xiaolu, Gao, Haitao, Ren, Lixin, Gu, Junfei, Zhang, Yanping, Zhang, Yong
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024097/
https://ncbi.nlm.nih.gov/pubmed/24885368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-308
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