DksA Guards Elongating RNA Polymerase Against Ribosome-Stalling-Induced Arrest

In bacteria, translation-transcription coupling inhibits RNA polymerase (RNAP) stalling. We present evidence suggesting that, upon amino acid starvation, inactive ribosomes promote rather than inhibit RNAP stalling. We developed an algorithm to evaluate genome-wide polymerase progression independent...

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Bibliografiske detaljer
Main Authors: Zhang, Yan, Mooney, Rachel A., Grass, Jeffrey A., Sivaramakrishnan, Priya, Herman, Christophe, Landick, Robert, Wang, Jue D.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023959/
https://ncbi.nlm.nih.gov/pubmed/24606919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.02.005
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