DksA Guards Elongating RNA Polymerase Against Ribosome-Stalling-Induced Arrest

In bacteria, translation-transcription coupling inhibits RNA polymerase (RNAP) stalling. We present evidence suggesting that, upon amino acid starvation, inactive ribosomes promote rather than inhibit RNAP stalling. We developed an algorithm to evaluate genome-wide polymerase progression independent...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Yan, Mooney, Rachel A., Grass, Jeffrey A., Sivaramakrishnan, Priya, Herman, Christophe, Landick, Robert, Wang, Jue D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023959/
https://ncbi.nlm.nih.gov/pubmed/24606919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.02.005
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