BCR-ABL Affects STAT5A and STAT5B Differentially

Signal transducers and activators of transcription (STATs) are latent cytoplasmic transcription factors linking extracellular signals to target gene transcription. Hematopoietic cells express two highly conserved STAT5-isoforms (STAT5A/STAT5B), and STAT5 is directly activated by JAK2 downstream of s...

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Détails bibliographiques
Auteurs principaux: Schaller-Schönitz, Michael, Barzan, David, Williamson, Andrew J. K., Griffiths, John R., Dallmann, Iris, Battmer, Karin, Ganser, Arnold, Whetton, Anthony D., Scherr, Michaela, Eder, Matthias
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023949/
https://ncbi.nlm.nih.gov/pubmed/24836440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097243
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