BCR-ABL Affects STAT5A and STAT5B Differentially

Signal transducers and activators of transcription (STATs) are latent cytoplasmic transcription factors linking extracellular signals to target gene transcription. Hematopoietic cells express two highly conserved STAT5-isoforms (STAT5A/STAT5B), and STAT5 is directly activated by JAK2 downstream of s...

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Autores principales: Schaller-Schönitz, Michael, Barzan, David, Williamson, Andrew J. K., Griffiths, John R., Dallmann, Iris, Battmer, Karin, Ganser, Arnold, Whetton, Anthony D., Scherr, Michaela, Eder, Matthias
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023949/
https://ncbi.nlm.nih.gov/pubmed/24836440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097243
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