BCR-ABL Affects STAT5A and STAT5B Differentially

Signal transducers and activators of transcription (STATs) are latent cytoplasmic transcription factors linking extracellular signals to target gene transcription. Hematopoietic cells express two highly conserved STAT5-isoforms (STAT5A/STAT5B), and STAT5 is directly activated by JAK2 downstream of s...

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Autors principals: Schaller-Schönitz, Michael, Barzan, David, Williamson, Andrew J. K., Griffiths, John R., Dallmann, Iris, Battmer, Karin, Ganser, Arnold, Whetton, Anthony D., Scherr, Michaela, Eder, Matthias
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023949/
https://ncbi.nlm.nih.gov/pubmed/24836440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097243
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