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New β-Lactamase Inhibitors: a Therapeutic Renaissance in an MDR World

As the incidence of Gram-negative bacterial infections for which few effective treatments remain increases, so does the contribution of drug-hydrolyzing β-lactamase enzymes to this serious clinical problem. This review highlights recent advances in β-lactamase inhibitors and focuses on agents with n...

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Autors principals: Drawz, Sarah M., Papp-Wallace, Krisztina M., Bonomo, Robert A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023773/
https://ncbi.nlm.nih.gov/pubmed/24379206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00826-13
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