Susceptibility Breakpoints for Amphotericin B and Aspergillus Species in an In Vitro Pharmacokinetic-Pharmacodynamic Model Simulating Free-Drug Concentrations in Human Serum

Although conventional amphotericin B was for many years the drug of choice and remains an important agent against invasive aspergillosis, reliable susceptibility breakpoints are lacking. Three clinical Aspergillus isolates (Aspergillus fumigatus, Aspergillus flavus, and Aspergillus terreus) were tes...

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Autors principals: Elefanti, A., Mouton, J. W., Verweij, P. E., Zerva, L., Meletiadis, J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023763/
https://ncbi.nlm.nih.gov/pubmed/24514094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02661-13
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