Silymarin Reduces Profibrogenic Cytokines and Reverses Hepatic Fibrosis in Chronic Murine Schistosomiasis

In chronic schistosomiasis, hepatic fibrosis is linked to the portal hypertension that causes morbidity in Schistosoma mansoni infection. Silymarin (SIL) is a hepatoprotective and antioxidant medicament largely prescribed against liver diseases that has previously been shown to prevent fibrosis duri...

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Main Authors: Mata-Santos, Hílton Antônio, Dutra, Fabianno Ferreira, Rocha, Carolina Carneiro, Lino, Fabiana Gonçalves, Xavier, Fabiola Ramos, Chinalia, Leandro Andrade, Hossy, Bryan Hudson, Castelo-Branco, Morgana Teixeira Lima, Teodoro, Anderson Junger, Paiva, Claudia N., Pyrrho, Alexandre dos Santos
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Experimental Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023717/
https://ncbi.nlm.nih.gov/pubmed/24449779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01936-13
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