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An inhibitor of p34cdc2/cyclin B that regulates the G2/M transition in Xenopus extracts.

The activity of maturation-promoting factor (MPF), a protein kinase complex composed of p34cdc2 and cyclin B, is undetectable during interphase but rises abruptly at the G2/M transition to induce mitosis. After the synthesis of cyclin B, the suppression of MPF activity before mitosis has been attrib...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Lee, T H, Kirschner, M W
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40236/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8552637/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.1.352
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