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Calpain: a molecule to induce AIF-mediated necroptosis in RGC-5 following elevated hydrostatic pressure

BACKGROUND: RIP3 (Receptor-interacting protein 3) pathway was mainly described as the molecular mechanism of necroptosis (programmed necrosis). But recently, non-RIP3 pathways were found to mediate necroptosis. We deliberate to investigate the effect of calpain, a molecule to induce necroptosis as r...

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Detalhes bibliográficos
Main Authors: Shang, Lei, Huang, Ju-Fang, Ding, Wei, Chen, Shuang, Xue, Li-Xiang, Ma, Ruo-Fei, Xiong, Kun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023497/
https://ncbi.nlm.nih.gov/pubmed/24884644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-15-63
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