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PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistance

Prostate cancer (PCa) is the second most common malignancy among men in the world. Castration-resistant prostate cancer (CRPC) is the lethal form of the disease, which develops upon resistance to first line androgen deprivation therapy (ADT). Emerging evidence demonstrates a key role for the PI3K-AK...

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Detalhes bibliográficos
Main Authors: Edlind, Merritt P, Hsieh, Andrew C
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023363/
https://ncbi.nlm.nih.gov/pubmed/24759575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1008-682X.122876
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