Comet assay in reconstructed 3D human epidermal skin models—investigation of intra- and inter-laboratory reproducibility with coded chemicals

Reconstructed 3D human epidermal skin models are being used increasingly for safety testing of chemicals. Based on EpiDerm™ tissues, an assay was developed in which the tissues were topically exposed to test chemicals for 3h followed by cell isolation and assessment of DNA damage using the comet ass...

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Bibliografiske detaljer
Main Authors: Reus, Astrid A., Reisinger, Kerstin, Downs, Thomas R., Carr, Gregory J., Zeller, Andreas, Corvi, Raffaella, Krul, Cyrille A.M., Pfuhler, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Original Manuscript
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023299/
https://ncbi.nlm.nih.gov/pubmed/24150594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/get051
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