Parvalbumin Cell Ablation of NMDA-R1 Causes Increased Resting Network Excitability with Associated Social and Self-Care Deficits

NMDA-receptor (NMDAR) hypofunction is strongly implicated in the pathophysiology of schizophrenia. Several convergent lines of evidence suggest that net excitation propagated by impaired NMDAR signaling on GABAergic interneurons may be of particular interest in mediating several aspects of schizophr...

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Detalhes bibliográficos
Main Authors: Billingslea, Eddie N, Tatard-Leitman, Valerie M, Anguiano, Jaynie, Jutzeler, Catherine R, Suh, Jimmy, Saunders, John A, Morita, Susumu, Featherstone, Robert E, Ortinski, Pavel I, Gandal, Michael J, Lin, Robert, Liang, Yuling, Gur, Raquel E, Carlson, Gregory C, Hahn, Chang-Gyu, Siegel, Steven J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023157/
https://ncbi.nlm.nih.gov/pubmed/24525709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.7
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