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Topological Localization of Monomeric C-reactive Protein Determines Proinflammatory Endothelial Cell Responses

The activation of endothelial cells (ECs) by monomeric C-reactive protein (mCRP) has been implicated in contributing to atherogenesis. However, the potent proinflammatory actions of mCRP on ECs in vitro appear to be incompatible with the atheroprotective effects of mCRP in a mouse model. Because mCR...

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Bibliographic Details
Main Authors: Filep, János G., Potempa, Lawrence A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022894/
https://ncbi.nlm.nih.gov/pubmed/24711458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.555318
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