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Base Excision Repair of Tandem Modifications in a Methylated CpG Dinucleotide

Cytosine methylation and demethylation in tracks of CpG dinucleotides is an epigenetic mechanism for control of gene expression. The initial step in the demethylation process can be deamination of 5-methylcytosine producing the TpG alteration and T:G mispair, and this step is followed by thymine DNA...

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Detalhes bibliográficos
Main Authors: Sassa, Akira, Çağlayan, Melike, Dyrkheeva, Nadezhda S., Beard, William A., Wilson, Samuel H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022870/
https://ncbi.nlm.nih.gov/pubmed/24695738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.557769
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