Structural and Biophysical Characterization of Murine Rif1 C Terminus Reveals High Specificity for DNA Cruciform Structures

Mammalian Rif1 is a key regulator of DNA replication timing, double-stranded DNA break repair, and replication fork restart. Dissecting the molecular functions of Rif1 is essential to understand how it regulates such diverse processes. However, Rif1 is a large protein that lacks well defined functio...

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Bibliografiske detaljer
Main Authors: Sukackaite, Rasa, Jensen, Malene Ringkjøbing, Mas, Philippe J., Blackledge, Martin, Buonomo, Sara B., Hart, Darren J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022862/
https://ncbi.nlm.nih.gov/pubmed/24634216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.557843
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