Intramolecular Interactions That Induce Helical Rearrangement upon Rhodopsin Activation: LIGHT-INDUCED STRUCTURAL CHANGES IN METARHODOPSIN II(a) PROBED BY CYSTEINE S-H STRETCHING VIBRATIONS

Rhodopsin undergoes rearrangements of its transmembrane helices after photon absorption to transfer a light signal to the G-protein transducin. To investigate the mechanism by which rhodopsin adopts the transducin-activating conformation, the local environmental changes in the transmembrane region w...

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Main Authors: Yamazaki, Yoichi, Nagata, Tomoko, Terakita, Akihisa, Kandori, Hideki, Shichida, Yoshinori, Imamoto, Yasushi
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Molecular Biophysics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022853/
https://ncbi.nlm.nih.gov/pubmed/24692562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.527606
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