Clostridium perfringens epsilon toxin mutant Y30A-Y196A as a recombinant vaccine candidate against enterotoxemia

Epsilon toxin (Etx) is a β-pore-forming toxin produced by Clostridium perfringens toxinotypes B and D and plays a key role in the pathogenesis of enterotoxemia, a severe, often fatal disease of ruminants that causes significant economic losses to the farming industry worldwide. This study aimed to d...

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Autors principals: Bokori-Brown, Monika, Hall, Charlotte A., Vance, Charlotte, Fernandes da Costa, Sérgio P., Savva, Christos G., Naylor, Claire E., Cole, Ambrose R., Basak, Ajit K., Moss, David S., Titball, Richard W.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Science 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022833/
https://ncbi.nlm.nih.gov/pubmed/24709588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.03.079
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