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The Complexity of the IGF1 Gene Splicing, Posttranslational Modification and Bioactivity

The insulinlike growth factor-I (IGF-I) is an important factor which regulates a variety of cellular responses in multiple biological systems. The IGF1 gene comprises a highly conserved sequence and contains six exons, which give rise to heterogeneous mRNA transcripts by a combination of multiple tr...

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Bibliografiske detaljer
Main Authors: Philippou, Anastassios, Maridaki, Maria, Pneumaticos, Spiros, Koutsilieris, Michael
Format: Artigo
Sprog:Inglês
Udgivet: ScholarOne 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022784/
https://ncbi.nlm.nih.gov/pubmed/24637928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2014.00011
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