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Maternal Separation Enhances Conditioned Fear and Decreases the mRNA Levels of the Neurotensin Receptor 1 Gene with Hypermethylation of This Gene in the Rat Amygdala

Stress during postnatal development is associated with an increased risk for depression, anxiety disorders, and substance abuse later in life, almost as if mental illness is able to be programed by early life stressors. Recent studies suggest that such “programmed” effects can be caused by epigeneti...

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Detalhes bibliográficos
Main Authors: Toda, Hiroyuki, Boku, Shuken, Nakagawa, Shin, Inoue, Takeshi, Kato, Akiko, Takamura, Naoki, Song, Ning, Nibuya, Masashi, Koyama, Tsukasa, Kusumi, Ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022612/
https://ncbi.nlm.nih.gov/pubmed/24831231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097421
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