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Bothrops jararaca Venom Metalloproteinases Are Essential for Coagulopathy and Increase Plasma Tissue Factor Levels during Envenomation

BACKGROUND/AIMS: Bleeding tendency, coagulopathy and platelet disorders are recurrent manifestations in snakebites occurring worldwide. We reasoned that by damaging tissues and/or activating cells at the site of the bite and systemically, snake venom toxins might release or decrypt tissue factor (TF...

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Библиографические подробности
Главные авторы: Yamashita, Karine M., Alves, André F., Barbaro, Katia C., Santoro, Marcelo L.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022520/
https://ncbi.nlm.nih.gov/pubmed/24831016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002814
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