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Bothrops jararaca envenomation: Pathogenesis of hemostatic disturbances and intravascular hemolysis

To attain fully functional biological activity, vitamin-K dependent coagulation factors (VKDCF) are γ-carboxylated prior to secretion from liver. Warfarin impairs the γ-carboxylation, and consequently their physiological function. Bothrops jararaca snake venom (BjV) contains several activators of bl...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Senise, Luana V, Yamashita, Karine M, Santoro, Marcelo L
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935303/
https://ncbi.nlm.nih.gov/pubmed/26080462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370215590818
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