Deregulation of Microcephalin and ASPM Expression Are Correlated with Epithelial Ovarian Cancer Progression

Mutations in the MCPH1 (Microcephalin) and ASPM (abnormal spindle-like microcephaly associated) genes cause primary microcephaly. Both are centrosomal associated proteins involved in mitosis. Microcephalin plays an important role in DNA damage response and ASPM is required for correct division of pr...

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Bibliographic Details
Main Authors: Alsiary, Rawiah, Brüning-Richardson, Anke, Bond, Jacquelyn, Morrison, Ewan E., Wilkinson, Nafisa, Bell, Sandra M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022499/
https://ncbi.nlm.nih.gov/pubmed/24830737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097059
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