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Absence of Perilipin 2 Prevents Hepatic Steatosis, Glucose Intolerance and Ceramide Accumulation in Alcohol-Fed Mice

BACKGROUND: Perilipin 2 (Plin2) is a lipid droplet protein that has roles in both lipid and glucose homeostasis. An increase in Plin2 in liver is associated with the development of steatosis, glucose intolerance, and ceramide accumulation in alcoholic liver disease. We investigated the role of Plin2...

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Detalhes bibliográficos
Main Authors: Carr, Rotonya M., Peralta, Giselle, Yin, Xiaoyan, Ahima, Rexford S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022498/
https://ncbi.nlm.nih.gov/pubmed/24831094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097118
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