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Integrated transcriptome analysis across mitochondrial disease etiologies and tissues improves understanding of common cellular adaptations to respiratory chain dysfunction

Mitochondrial diseases are heterogeneous, multi-systemic disorders for which mechanistic understanding is limited. To investigate common downstream effects of primary respiratory chain dysfunction on global gene expression and pathway regulation, we reanalyzed transcriptome datasets from all publicl...

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Hlavní autoři: Zhang, Zhe, Falk, Marni J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022474/
https://ncbi.nlm.nih.gov/pubmed/24569120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2014.02.012
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