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Integrated transcriptome analysis across mitochondrial disease etiologies and tissues improves understanding of common cellular adaptations to respiratory chain dysfunction

Mitochondrial diseases are heterogeneous, multi-systemic disorders for which mechanistic understanding is limited. To investigate common downstream effects of primary respiratory chain dysfunction on global gene expression and pathway regulation, we reanalyzed transcriptome datasets from all publicl...

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Detalhes bibliográficos
Main Authors: Zhang, Zhe, Falk, Marni J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022474/
https://ncbi.nlm.nih.gov/pubmed/24569120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2014.02.012
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